… In addition, CXCL10 is produced by β-cells, and suppresses β-cell … , CXCL10/CXCR3 system
plays a decisive role in the pathogenesis of T1D. Here we review CXCL10/CXCR3 system, …

… we believe that the CXCL10/CXCR3 system plays a decisive role in the pathogenesis of type
1 diabetes. In this short review article, we take a closer look at the CXCL10/CXCR3 system, …

… That, or so it seemed, was to be the fate of the chemokine CXCL10 and its receptor CXCR3
as promising therapeutic targets in type 1 diabetes (T1D). Yet in this issue of Diabetes, Lasch …

… We examined serum CXCL10 levels in two fulminant type 1 diabetic patients (cases 1 and
2) using enzyme-linked immunosorbent assay, as previously described (26). Serum samples …

… (CXC motif) receptor 3 (CXCR3). CXCL10 and its receptor, CXCR3, appear to contribute
to the pathogenesis of many autoimmune diseases, organ specific (such as type 1 diabetes, …

… Although we did not find an association of the CXCL9 and CXCL10 polymorphisms with
type 1 diabetes in the German population, we cannot discard their role in other populations or …

… recent-onset type 1 diabetes and five control subjects without diabetes. Islet cell … CXCL10
and CXCR3 in human autoimmune type 1 diabetes, we investigated the expression of CXCL10 …

… CXCL10 and CXCR3 expression in pancreatic islets of a new-onset type 1 diabetes patient
… similar to a very recent report on fulminant diabetes and enterovirus infection [29]. A role for …

… in type 1 diabetes (T1D). Blockade of CXCL10 or genetic deletion of its receptor CXCR3 …
As an alternative to the use of neutralizing monoclonal antibodies to CXCL10 or CXCR3 we …

… islets from patients suffering from type 1 diabetes (T1D) and … the chemokine CXCL10 and
its receptor CXCR3 on activated … blockade of the CXCL10/CXCR3 chemokine axis halts T1D …